Celtaxsys Acquires Clinical Stage Innate Immunity Drug
for Inflammation

San Francisco, Calif., January 5, 2012 /PRNewswire / -- Celtaxsys, Inc. a privately held biotechnology company announced today that it has acquired CTX-4430 (formerly EP-501), a clinical stage drug candidate that inhibits the pro-inflammatory enzyme Leukotriene A4 Hydrolase (LTA4H), from Estrellita Pharmaceuticals, Inc.

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Dr. H. Daniel Perez
Joins Celtaxsys Board of Directors

SAN FRANCISCO, June 6, 2011 /PRNewswire/ -- Celtaxsys, Inc., a private biopharmaceutical company defining new therapeutics in inflammation, announces the appointment of life sciences industry veteran, H. Daniel Perez, M.D., to its Board of Directors (BOD).

"We are delighted that Dr. Perez has joined the Celtaxsys team," says Dr. Michael R. Hanley, CEO and Chairman of the Board of Celtaxsys. "He brings more than 25 years of high level pharmaceutical executive experience to the BOD, in addition to scientific and commercial accomplishments related to Celtaxsys' mission. We look forward to working closely with Dr. Perez."

"I am excited about the opportunities that an innate immunity company brings to the therapeutic field," commented Dr. Perez. "This is an area that is close to my heart and has not received the attention that it deserves. I believe Celtaxsys will bring new paradigms to the forefront of innovative therapeutics."

H. Daniel Perez, M.D., is a Venture Partner with Bay City Capital, and was previously President and CEO of Berlex Biosciences until its acquisition by Bayer in 2006. He is on the Board of Directors of Cleveland Biolabs (a public company, CBLI), Presidio Pharmaceuticals, and F&P Pharmaceuticals (privately held companies), the Scientific Advisory Boards of Cardium (a public company, CDTP, CXM), Vertex Pharmaceuticals neurodegenerative diseases (VRTX, Nasdaq), Glaxo GSK, (Neuroinflammation, China) and the Advisory Board for the Gladstone Institutes at the University of California, San Francisco (UCSF). Dr. Perez received his medical degree in Buenos Aires, Argentina and completed his medical training at Beth Israel-Mount Sinai and New York University, in New York City. Dr. Perez has published extensively and is the author of a number of patents.

Michael Hanley, Ph.D. 
Chief Executive Officer

ATLANTA, Dec. 2, 2010 /PRNewswire/ -- Georgia -based drug discovery start-up, Celtaxsys, Inc. is pleased to announce that Dr. Michael Hanley has joined the company as its new Chief Executive Officer and Chairman of the Board of Directors.

Dr. Hanley has served on both the Scientific Advisory Board and Board of Directors of Celtaxsys since 2007. Dr. Hanley brings more than 20 years of managerial experience in the international life science industry including drug discovery, product development, and production. He was most recently the Chief Scientific Officer for Amylin Pharmaceuticals where he was responsible for discovery research and preclinical development.

"We are very pleased that Dr. Hanley has joined us as CEO," says William Reddick, CFO and Founder of Celtaxsys. "His background as an industry leader, and as an innovative drug hunter, with direct knowledge of our area of research, are qualities well-matched to our needs. We are delighted in the strengths he brings to Celtaxsys."

"Over the last few years I have gained an insight into the innovative technology and exciting research and development that are at the core of Celtaxsys. I look forward towards building long-term, future success and stakeholder value at the Company," says Michael Hanley.

From 1981 to 1997, Dr. Hanley held faculty positions at Imperial College, London, the Medical Research Council Laboratories, Cambridge, and the University of California at Davis, where he was Professor of Biological Chemistry. From 1997 to 2003, he was a senior consultant for healthcare investors in the venture capital and banking communities and for biotechnology companies such as Cell Therapeutics, Zymogenetics, Elan Pharmaceuticals, and Chiron. Dr. Hanley has founded several start-ups, such as Resolvyx Pharmaceuticals and Psylin Neurosciences, and is currently on boards of Aileron Therapeutics, Metabolic Solutions Development Company, Isogenica, and Pieris. He received a bachelor's degree in Biochemistry and a Ph.D. in Molecular Biology from the University of California, Berkeley.

Eric Springman, Ph.D.
Chief Scientific Officer

ATLANTA, GA — December 9, 2009 – Celtaxsys, Inc., a privately held biopharmaceutical company focused on novel mechanisms of inflammation therapy, announced that it has hired Eric B. Springman, Ph.D. to the position of Chief Scientific Officer. In this new role, Dr. Springman will lead Celtaxsys’ research and drug discovery activities, and will serve on the company’s management team.

Before joining Celtaxsys, Dr. Springman was a Senior Director at Locus Pharmaceuticals, where he played a leading role in each of the company’s three IND programs. During his tenure at Locus Dr. Springman was also responsible for founding the Biology Department, integrating Structural Biology into the technology platform, garnering significant grant funding for the company’s research, and revitalizing the company’s Discovery Technologies core. Prior to Locus, Dr. Springman held positions of increasing responsibility at Roche Pharmaceuticals in Palo Alto, CA, including Acting Head of the Arthritis Therapy Area. Prior to that he worked at Arris/Axys Pharmaceuticals where he was co-leader of the partnered project resulting in Merck's Phase III drug candidate, Odanacatib. In 2007, Dr. Springman was appointed by Governor Edward Rendell to the Pennsylvania Drug, Device & Cosmetics Board.

Dr. Springman received a B.A. in Chemistry/Biology from Florida Atlantic University, a Ph.D. in Biophysics from Florida State University, and was an NRSA and American Lung Association Post-Doctoral Fellow in Pharmacology at Vanderbilt University Medical Center. “I am excited to join Celtaxsys and help lead the Company’s efforts to commercialize its platform assets, with particular focus on selecting candidate compounds to move expeditiously into the clinic.” said Dr. Springman.

“We are delighted that Eric is joining us at such an exciting time, as we move into development of our anti-inflammatory compounds,” said Bill Reddick, President of Celtaxsys. “Eric brings a wealth of experience leading drug discovery R&D operations, and his depth of knowledge will be highly valued as our team continues to advance our therapeutic programs”.

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